비타민과 무기질의 새로운 영양학적 의미
비타민과 무기질의 새로운 영양학적 의미.PDF비타민과 무기질의 새로운 영양학적 의미
경상대학교 의과대학 소아과학교실
윤희상
Abstract
New Nutritional Concepts of Vitamins and Minerals
Hee-Shang Youn, M.D.
Department of Pediatrics, Gyeongsang National University College of Medicine, Jinju, Korea
Nowadays, the nutritional deficits are rarely seen in Korea. However, an increased availability of the
highly palatable energy dense, nutrient-poor foods increases the risks of obesity and deficits of vitamins
and minerals in the general population. Also, optimum intake of vitamins and minerals, which
varies with age and genetic back ground, might not suffice the poor, young, obese, and elderly people.
Young girls and individuals participating in weight reductions and aesthetic components are
prone to micronutrient deficiencies because they restrict food intake and specific micronutrient rich
foods. An inadequate intake of vitamins or minerals is associated with reduced physical performance
and exercise capacity, increased obesity, decreased cognitive function, increased DNA damages such
as single- and double-stranded breaks or oxidative DNA lesions, and accelerated aging process and
increased neuronal damages with mitochondrial oxidative decay. Most of these deleterious effects of
the deficit could be prevented by a one tablet of multivitamins with a good balanced diet. High dose
B vitamins are frequently administered to overcome the metabolic inadequacy to the people with the
less functional enzymes with increased Km values for their coenzymes due to the single gene mutation
or due to the single nucleotide polymorphisms. And some certain antioxidant vitamins are also
used in large quantities to overcome the oxidative stress and to repair the damages. In this review,
new nutritional concepts of some vitamins and minerals, which are widely used and useful for the
children, will be discussed. (Korean J Pediatr 2005;48:1295-1309)